Radiofrequency ablation of atrial fibrillation
Autor: | ES Tan, Acp Wiesfeld, van Dirk Veldhuisen, van Isabelle Gelder, Hjgm Crijns |
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Přispěvatelé: | Cardiovascular Centre (CVC) |
Jazyk: | angličtina |
Rok vydání: | 2004 |
Předmět: |
Male
medicine.medical_specialty Time Factors Heart disease Radiofrequency ablation medicine.medical_treatment Catheter ablation PULMONARY VEINS Cardioversion THERAPY law.invention Coronary artery disease Electrocardiography INITIATION law Internal medicine medicine Humans FLUTTER atrial fibrillation CATHETER ABLATION ANATOMIC APPROACH business.industry Patient Selection Atrial fibrillation Middle Aged medicine.disease Ablation Surgery Catheter CARDIOVERSION Cardiology Female radiofrequency ablation Cardiology and Cardiovascular Medicine business Anti-Arrhythmia Agents Follow-Up Studies |
Zdroj: | International Journal of Cardiology, 93(2-3), 231-237. ELSEVIER IRELAND LTD |
ISSN: | 0167-5273 |
Popis: | Twenty-five patients (16 males, mean age 46 years.) underwent radiofrequency ablation because of either paroxysmal (13 patients) or persistent atrial fibrillation (12 patients). Ablation aimed at earliest activation of spontaneous and catheter-induced repetitive ectopy in left and right atria and appendages, and pulmonary veins. Catheter-induced repetitive ectopy was defined as acute onset of a burst of rapid atrial premature beats on touching the wall, sustained irritability while at the spot and acute termination of rapid activity upon release of the catheter. Post-ablation patients received antiarrhythmic drugs to prevent tachycardias, thereby allowing reversal of atrial remodeling. Results: Lone atrial fibrillation was present in 19 patients, 4 patients had hypertension and 2 patients coronary artery disease with preserved left ventricular function. The median duration of the history of atrial fibrillation was 4 years (range 1-14 years) and the median number of antiarrhythmic drug failures 5 (range 1-6). Ablation was successful, i.e. no recurrences of atrial fibrillation with or without antiarrhythmic drugs in eight patients (32%) during a median follow-up of 28 months (range 18-52). The median number of foci was 3 (range 2-6) and 2 (range 1-7) in the successfully and unsuccessfully treated patients, respectively. Minor complications occurred in three patients. Conclusions: Radiofrequency ablation of atrial fibrillation aiming at spontaneous and catheter-induced repetitive ectopy is a safe procedure. However, it is only successful in one third of the patients. Further investigations are warranted to identify the ideal patient, as well as to develop better ablation strategies. (C) 2003 Elsevier Ireland Ltd. All rights reserved. |
Databáze: | OpenAIRE |
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