Comparison of Dental Health of Patients with Head and Neck Cancer Receiving IMRT vs Conventional Radiation
| Autor: | Marilene B. Wang, Sassan Rafizadeh, Victor M. Duarte, Yuan F. Liu, Vishad Nabili, Tracey Tajima |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Adult
Male Mucositis Osteoradionecrosis medicine.medical_treatment Dentistry Dental Caries Xerostomia Cohort Studies Patient Education as Topic Oral and maxillofacial pathology medicine Humans Aged Retrospective Studies Aged 80 and over Dental Treatment Plan business.industry Dental health Head and neck cancer Stomatognathic Diseases Middle Aged medicine.disease Radiation therapy stomatognathic diseases Otorhinolaryngology Head and Neck Neoplasms Cohort Female Surgery Radiotherapy Intensity-Modulated business |
| Zdroj: | Otolaryngology–Head and Neck Surgery. 150:81-86 |
| ISSN: | 1097-6817 0194-5998 |
| DOI: | 10.1177/0194599813509586 |
| Popis: | To analyze the dental health of patients with head and neck cancer who received comprehensive dental care after intensity-modulated radiation therapy (IMRT) compared with radiation therapy (RT).Historical cohort study.Veteran Affairs (VA) hospital.In total, 158 patients at a single VA hospital who were treated with RT or IMRT between 2003 and 2011 were identified. A complete dental evaluation was performed prior to radiation treatment, including periodontal probing, tooth profile, cavity check, and mobility. The dental treatment plan was formulated to eliminate current and potential dental disease. The rates of dental extractions, infections, caries, mucositis, xerostomia, and osteoradionecrosis (ORN) were analyzed, and a comparison was made between patients treated with IMRT and those treated with RT.Of the 158 patients, 99 were treated with RT and 59 were treated with IMRT. Compared with those treated with IMRT, significantly more patients treated with RT exhibited xerostomia (46.5% vs 16.9%; P.001; odds ratio [OR], 0.24; 95% confidence interval [CI], 0.11-0.52), mucositis (46.5% vs 16.9%; P.001; OR, 0.24; 95% CI, 0.11-0.52), and ORN (10.1% vs 0%; P = .014; OR, 0.07; 95% CI, 0.00-1.21). However, significantly more patients treated with IMRT were edentulous by the conclusion of radiation treatment (32.2% vs 11.1%; P = .002; OR, 3.8; 95% CI, 1.65-8.73).Patients who were treated with IMRT had fewer instances of dental disease, more salivary flow, and fewer requisite posttreatment extractions compared with those treated with RT. The number of posttreatment extractions has been reduced with the advent of IMRT and more so with a complete dental evaluation prior to treatment. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text