Cough and airway clearance in Duchenne muscular dystrophy
| Autor: | Federica Camela, Giampaolo Ricci, Marcella Gallucci |
|---|---|
| Přispěvatelé: | Camela, F, Gallucci, M, Ricci, G |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Pulmonary and Respiratory Medicine
Resuscitator Duchenne muscular dystrophy Pulmonary Atelectasis Respiratory Therapy Neuromuscular disease Maximal Respiratory Pressures Exacerbation Respiratory Muscle Mechanical insufflator–exsufflator Vital Capacity Atelectasis 03 medical and health sciences 0302 clinical medicine Physical Therapy Modalitie medicine Humans Respiratory Tract Infection 030212 general & internal medicine Respiratory Tract Infections Physical Therapy Modalities business.industry Pulmonary Atelectasi Maximal Respiratory Pressure medicine.disease Glossopharyngeal breathing Respiratory Muscles Muscular Dystrophy Duchenne 030228 respiratory system Respiratory failure Cough Anesthesia Pediatrics Perinatology and Child Health Breathing Quality of Life Air stacking Peak cough flow business Respiratory Insufficiency Human |
| Popis: | People with Duchenne muscular dystrophy (DMD), develop a respiratory muscle weakness that results in weakened cough, airway clearance impairment and over time respiratory failure and death. Assessment of cough effectiveness through vital capacity, peak cough flow and maximal inspiratory and expiratory pressures has been used to identify the optimal timing of cough augmentation techniques initiation. The choice of therapies depends on physician knowledge, and patient/care giver abilities. The purpose of this review is to clarify mechanisms of action, benefits and disadvantages of available techniques, such as manual cough-assisting manoeuvres, glossopharyngeal breathing, air stacking by resuscitator bag or by volume-cycle ventilator, and mechanical insufflator-exsufflator. Mechanisms of mucus mobilization, like intrapulmonary percussive ventilation, may have a therapeutic role in the case of persistent atelectasis. It is also crucial to recognize the initial phase of an acute respiratory exacerbation, increase the use of these techniques which may reduce morbidity and mortality. |
| Databáze: | OpenAIRE |
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