A Review on Delivery and Bioavailability Enhancement Strategies of Azithromycin

Autor:	Pallavi Swarup, Gopal Prasad Agrawal
Rok vydání:	2022
Předmět:	Biological Products Solubility Drug Discovery Biological Availability Water Molecular Medicine Azithromycin Anti-Bacterial Agents
Zdroj:	ASSAY and Drug Development Technologies. 20:251-257
ISSN:	1557-8127 1540-658X
DOI:	10.1089/adt.2022.036
Popis:	Azithromycin (AZI) belongs to the class of macrolide antibiotics that has limited water solubility and belongs to Biopharmaceutical Classification System Class II. Dissolution is the rate-limiting step in the absorption process of AZI. Several approaches have been investigated for enhancing the bioavailability of poorly soluble drugs. This review intends to explore the various strategies that have been investigated for improving the solubility and/or bioavailability of AZI and the delivery systems that have been designed for delivery of AZI in ocular fluid.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cce8789b697eeaf11d9a6e3ebcf5929 https://doi.org/10.1089/adt.2022.036 Zobrazit plný text záznamu