Deep Ulcers in the Ileum Associated with Mycophenolate Mofetil
| Autor: | Akira Sonoda, Kensuke Fukuda, Kurato Wada, Tadayoshi Okimoto, Kazuhisa Okamoto, Kazunari Murakami, Mitsutaka Shuto, Kazuhiro Mizukami, Ryo Ogawa |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Graft Rejection
Male medicine.medical_specialty Case Report Ileum 030230 surgery Mycophenolate Gastroenterology Mycophenolic acid 03 medical and health sciences 0302 clinical medicine Internal medicine Internal Medicine medicine Humans gastrointestinal toxicity Ulcer Kidney transplantation Mizoribine biology Ileal Diseases business.industry C-reactive protein mycophenolate mofetil General Medicine renal transplantation Middle Aged Mycophenolic Acid medicine.disease ileal ulcer Kidney Transplantation Transplantation Diarrhea C-Reactive Protein medicine.anatomical_structure biology.protein 030211 gastroenterology & hepatology medicine.symptom business Immunosuppressive Agents medicine.drug |
| Zdroj: | Internal Medicine |
| ISSN: | 1349-7235 0918-2918 |
| DOI: | 10.2169/internalmedicine.8815-17 |
| Popis: | A 54-year-old man was treated with mycophenolate mofetil (MMF) after undergoing living donor renal transplantation. Two years later, he experienced repeated episodes of diarrhea, and his C-reactive protein (CRP) level was found to be 12.63 mg/dL. Ileocolonoscopy showed multiple deep, punched-out ulcers that were similar to Behçet's disease (BD) and cytomegalovirus (CMV) in the ileum. CMV infection was suspected. However, anti-cytomegalovirus agents were ineffective. The patient was subsequently diagnosed with gastrointestinal toxicity of MMF and MMF was switched to mizoribine. His symptoms improved immediately, and his CRP level normalized. Six months later, the patient's mucosa was healed. |
| Databáze: | OpenAIRE |
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