Transfer factor is ineffective in amyotrophic lateral sclerosis
| Autor: | Marcelo R. Olarte, John Zabriskie, Joanne C. Gersten, Lewis P. Rowland |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
Adult
Male medicine.medical_specialty business.industry Transfer factor Amyotrophic Lateral Sclerosis Significant difference Neurological function Transfer Factor Middle Aged medicine.disease Placebo Rating score Clinical trial Neurology Internal medicine medicine Physical therapy Humans Female Statistical analysis Neurology (clinical) Amyotrophic lateral sclerosis business Aged |
| Zdroj: | Annals of Neurology. 5:385-388 |
| ISSN: | 1531-8249 0364-5134 |
| DOI: | 10.1002/ana.410050413 |
| Popis: | Sixty-six patients with amyotrophic lateral sclerosis (ALS) participated in a double-blind, placebo-controlled study of transfer factor. A structured rating score of neurological function was recorded after each monthly administration of transfer factor or placebo. Statistical analysis of mean scores for all patients and for those with specific clinical abnormalities showed no significant difference between the two groups. There was no evidence of therapeutic value for transfer factor. During the observation period of nearly one year, more than two-thirds of the deterioration occurred in the first six months. Meaningful clinical trials of other potential therapeutic agents could probably be conducted within six months in double-blind crossover trials. |
| Databáze: | OpenAIRE |
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