Electroacupuncture versus Moxibustion for Irritable Bowel Syndrome: A Randomized, Parallel-Controlled Trial

Autor: An-Qi Wang, Chunhui Bao, Jin-Hua Lu, Jie Sun, Ji-Meng Zhao, Yin Shi, Yue-Hua Chen, Rong Ji, Huangan Wu, Xiao-Jun Yin, Xing-Kui Chen
Rok vydání: 2015
Předmět:
Zdroj: Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-Based Complementary and Alternative Medicine, Vol 2015 (2015)
ISSN: 1741-4288
1741-427X
DOI: 10.1155/2015/361786
Popis: Objective.To compare the impacts of electroacupuncture (EA) and mild moxibustion (Mox) on patients with irritable bowel syndrome (IBS).Method.Eighty-two IBS patients were randomly allocated into EA group (n=41) and Mox group (n=41) and received corresponding interventions for four weeks. Before and after the treatment, the Visual Analogue Scale for Irritable Bowel Syndrome (VAS-IBS) was used to evaluate the gastrointestinal symptoms and mental well-being; and the expression of serotonin (5-hydroxytryptamine, 5-HT), 5-HT3receptor (5-HT3R), and 5-HT4receptor (5-HT4R) in sigmoid mucosal tissue were detected.Results. Both EA and Mox can radically improve the total VAS-IBS score (P<0.05), and EA was found to be more effective in ameliorating the symptom of constipation, while Mox was found to be more effective in ameliorating the symptom of diarrhoea. The abnormal expressions of 5-HT, 5-HT3R, and 5-HT4R in both groups were significantly improved after the treatments (allP<0.05), and EA was superior to Mox in regulating the abnormally decreased 5-HT4R expression in IBS patients with constipation (P<0.05).Conclusion. Electroacupuncture and mild moxibustion were both effective in improving IBS symptoms and modulate abnormal expressions of 5-HT, 5-HT3R, and 5-HT4R in the colonic tissue.
Databáze: OpenAIRE
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