Impact of the size of zona pellucida thinning area on vitrified-warmed cleavage-stage embryo transfers: a prospective, randomized study
| Autor: | Kenichiro Hiraoka, Tomoyo Kusuda, Shinichiro Okano, Toshitaka Horiuchi, Masayuki Kinutani, Kazuo Kinutani, Kaori Hiraoka |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Blastomeres endocrine system animal structures Pregnancy Rate Fertilization in Vitro Biology Cryopreservation Andrology Pregnancy Genetics medicine Humans Embryo Implantation Zona pellucida Zona Pellucida reproductive and urinary physiology Genetics (clinical) Laser assisted hatching Thinning urogenital system Lasers Obstetrics and Gynecology Embryo General Medicine Blastomere Embryo Transfer Embryo Mammalian Embryo transfer Pregnancy rate Assisted Reproduction Treatment Outcome medicine.anatomical_structure Reproductive Medicine embryonic structures Female Developmental Biology |
| Zdroj: | Journal of Assisted Reproduction and Genetics. 26:515-521 |
| ISSN: | 1573-7330 1058-0468 |
| Popis: | The aim of this study was to determine if the size of zona pellucida thinning area by laser assisted hatching could affect the rates of pregnancy and implantation for vitrified-warmed embryo transfers at the cleavage-stage.A total of 120 vitrified-warmed cleavage-stage embryo transfers were randomly assigned to either quarter or half of zona pellucida thinning group.The rates of clinical pregnancy (46.7 versus 25.0%) and implantation (32.0 versus 16.2%) were significantly greater in the half thinning group than in the quarter thinning group (P = 0.0218 and P = 0.0090, respectively).The results of this investigation show that, in vitrified-warmed embryo transfers at the cleavage-stage, the size of zona pellucida thinning area by laser assisted hatching impacts the rate of clinical pregnancy and implantation and that half of zona pellucida thinning significantly increases both of these results compared with quarter of zona pellucida thinning. |
| Databáze: | OpenAIRE |
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