May bioactive compounds from the olive fruit improve the postprandial insulin response in healthy adults?
| Autor: | Jose Maria Olmo-Peinado, Jose R Fernandez-Navarro, Rafael de la Torre, Estefania Sanchez-Rodriguez, Manuel Brenes, Laura Alejandra Vazquez-Aguilar, Monserrat Fito-Colomer, Angel Gil, María Isabel Covas, Juan Antonio Espejo-Calvo, María D. Mesa, Concepción Romero, Sara Biel-Glesson, Emilio Martínez de Victoria |
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| Přispěvatelé: | Centro para el Desarrollo Tecnológico Industrial (España), Junta de Andalucía, [Sanchez-Rodriguez, Estefania] Univ Granada, Biomed Res Ctr, Inst Nutr & Food Technol Jose Mataix, Dept Biochem & Mol Biol 2, Parque Tecnol Salud,Ave Conocimiento S-N, Granada 18100, Spain, [Alejandra Vazquez-Aguilar, Laura] Univ Granada, Biomed Res Ctr, Inst Nutr & Food Technol Jose Mataix, Dept Biochem & Mol Biol 2, Parque Tecnol Salud,Ave Conocimiento S-N, Granada 18100, Spain, [Gil, Angel] Univ Granada, Biomed Res Ctr, Inst Nutr & Food Technol Jose Mataix, Dept Biochem & Mol Biol 2, Parque Tecnol Salud,Ave Conocimiento S-N, Granada 18100, Spain, [Dolores Mesa, Maria] Univ Granada, Biomed Res Ctr, Inst Nutr & Food Technol Jose Mataix, Dept Biochem & Mol Biol 2, Parque Tecnol Salud,Ave Conocimiento S-N, Granada 18100, Spain, [Biel-Glesson, Sara] Fdn Publ Andaluza Invest Biosanitaria Andalucia O, Ave Madrid 15, Granada 18001, Spain, [Ramon Fernandez-Navarro, Jose] Fdn Publ Andaluza Invest Biosanitaria Andalucia O, Ave Madrid 15, Granada 18001, Spain, [Antonio Espejo-Calvo, Juan] Inst Calidad & Seguridad Alimentaria ICSA TECNOFO, Granada, Spain, [Maria Olmo-Peinado, Jose] Acer Campestres SL, Almendro 37, Jaen 23670, Spain, [de la Torre, Rafael] Hosp del Mar Res Inst IMIM, Integrat Pharmacol & Syst Neurosci Res Grp, Dr Aiguader 88, Barcelona 08003, Spain, [de la Torre, Rafael] Hlth Inst Carlos III, Spanish Biomed Res Networking Ctr Physiopathol Ob, Monforte de Lemos 3-5, Madrid 28029, Spain, [Fito-Colomer, Monserrat] Hlth Inst Carlos III, Spanish Biomed Res Networking Ctr Physiopathol Ob, Monforte de Lemos 3-5, Madrid 28029, Spain, [Gil, Angel] Hlth Inst Carlos III, Spanish Biomed Res Networking Ctr Physiopathol Ob, Monforte de Lemos 3-5, Madrid 28029, Spain, [Fito-Colomer, Monserrat] Hosp del Mar Res Inst IMIM, Cardiovasc Risk & Nutr Res Grp, Dr Aiguader 88, Barcelona 08003, Spain, [Isabel Covas, Maria] Handesbolag NUPROAS HB, NUPROAS Nutr Project Assessment, Nacka, Sweden, [Romero, Concepcion] Univ Campus Pablo de Olavide, Food Biotechnol Dept Inst Grasa IG CSIC, Bldg 46,Ctra Utrera Km 1, Seville 41013, Spain, [Brenes, Manuel] Univ Campus Pablo de Olavide, Food Biotechnol Dept Inst Grasa IG CSIC, Bldg 46,Ctra Utrera Km 1, Seville 41013, Spain, [Martinez de Victoria, Emilio] Univ Granada, Biomed Res Ctr, Inst Nutr & Food Technol Jose Mataix, Dept Physiol, Parque Tecnol Salud,Ave Conocimiento S-N, Granada 18100, Spain, [Gil, Angel] Ibs GRANADA, Biosanit Res Inst Granada, Granada 18014, Spain, [Dolores Mesa, Maria] Ibs GRANADA, Biosanit Res Inst Granada, Granada 18014, Spain, University of Granada (Spain), University of Guadalajara (Mexico), I + D FEDER-INTERCONNECTA (CDTI), Junta de Andalucia, Spain, ACER CAMPESTRES S.L., SAN FRANCISCO DE ASIS Coop, AGROINSUR S.L. |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Medicine (miscellaneous) 03 medical and health sciences Sensitivity 0404 agricultural biotechnology Insulin response TX341-641 Statistical analysis Sociology Gastrointestinal hormones 030109 nutrition & dietetics Nutrition and Dietetics biology Nutrition. Foods and food supply Garcia Insulin sensitivity 04 agricultural and veterinary sciences Triterpenic acids biology.organism_classification Oil 040401 food science Ghrelin Phenolic compounds Index Glucose Postprandial Pentacyclic triterpenes Humanities Olive oil Food Science |
| Zdroj: | Digibug: Repositorio Institucional de la Universidad de Granada Universidad de Granada (UGR) Digital.CSIC. Repositorio Institucional del CSIC instname Digibug. Repositorio Institucional de la Universidad de Granada Journal of Functional Foods, Vol 83, Iss, Pp 104561-(2021) |
| DOI: | 10.1016/j.jff.2021.104561 |
| Popis: | We are grateful for the support of participating volunteers, the personal of Virgen de las Nieves and San Cecilio general hospitals of Granada: Laura Campana Martin, Ma Victoria Martin Laguna and Ma Cruz Rico Prados who carried out technical work and sample preparation and Llenalia Garcia Fernandez who supervised the statistical analysis. We acknowledge the University of Granada (Spain) and the University of Guadalajara (Mexico) for the predoctoral scholarship of Laura Alejandra Vazquez Aguilar. The "NUTRAOLEUM Study" has been supported by the grant ITC-20131031 from the I + D FEDER-INTERCONNECTA (CDTI) and Junta de Andalucia, Spain". We thank ACER CAMPESTRES S.L., SAN FRANCISCO DE ASIS Coop and AGROINSUR S.L., for the funding financing provided for the development conduct of the clinical trial. Scope. The postprandial effects of virgin olive oils (VOOs) enriched with phenolic compounds and triterpenes from the olive fruit on plasma glucose and insulin (primary outcomes), and gastrointestinal hormones responses were evaluated in healthy adults. Methods and results: Single doses (30 mL) of three oils were evaluated: optimized polyphenols-rich VOO (OVOO); functional olive oil (FOO): OVOO enriched with triterpene acids; and VOO with low content of polyphenols. Postprandial plasma insulin release was lower after the intake of the FOO compared to VOO, while plasma glucose levels were lower after the intake of the VOO compared to OVOO. Matsuda's index of insulin sensitivity improved after the intake of FOO and OVOO, while the insulinogenic index and gastric inhibitory polypeptide (GIP) tended to improve after the intake of OVOO. Conclusion: The enrichment of VOOs with bioactive compounds from the olive fruit increases its benefits, improving postprandial insulin release and peripheral tissue sensitivity. University of Granada (Spain) University of Guadalajara (Mexico) I + D FEDER-INTERCONNECTA (CDTI) ITC-20131031 Junta de Andalucia European Commission ACER CAMPESTRES S.L. SAN FRANCISCO DE ASIS Coop AGROINSUR S.L. |
| Databáze: | OpenAIRE |
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