Content of Trace Elements in the Lymph and Blood during Pyrogenal-Induced Fever and Complete Freund’s Adjuvant-Induced Low-Grade Fever
| Autor: | F. I. Mukhutdinova, K. A. Triandafilov, L. V. Plaksina, R. Kh. Khafiz'yanova, D. A. Mukhutdinov |
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| Rok vydání: | 2009 |
| Předmět: |
Lipopolysaccharides
Fever Chemistry Freund's Adjuvant Trace element General Medicine Complete Freund's Adjuvant Systemic circulation General Biochemistry Genetics and Molecular Biology Rats Trace Elements Low-grade fever Selenium Zinc Lymphatic system Immunology Biological fluids Animals Thoracic duct lymph Magnesium Lymph Copper |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 148:852-855 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/s10517-010-0834-2 |
| Popis: | Experiments on rats showed that complete Freund's adjuvant-induced low-grade fever and pyrogenal-induced fever are accompanied by an increase in the content of Mn, Cu, Zn, and Se in the thoracic duct lymph. Our results indicate that the lymphatic system supplies trace elements to the circulation, which compensates for a deficiency in trace elements and maintains their systemic circulation. The decrease in the content of some trace elements in the blood during fever is probably associated with their excessive consumption (e.g., to maintain the antioxidant defense system). During experimental low-grade fever and pyrogenal-induced fever, the lymphatic system serves as the reservoir for trace elements and plays a role in the regulation of trace element balance in biological fluids. |
| Databáze: | OpenAIRE |
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