Effective connectivity underlying reward-based executive control

Autor: Bernadette Hippmann, Ronja Weiblen, Elinor Tzvi, Thomas F. Münte, Martin Göttlich, Sarah Jessen
Rok vydání: 2021
Předmět:
Adult
punishment
Punishment (psychology)
Decision Making
Affect (psychology)
behavioral disciplines and activities
050105 experimental psychology
03 medical and health sciences
Executive Function
Young Adult
0302 clinical medicine
Reward
medicine
Connectome
Humans
0501 psychology and cognitive sciences
Radiology
Nuclear Medicine and imaging
cognitive control
dynamic causal modeling
Anterior cingulate cortex
Research Articles
Cerebral Cortex
Motivation
Radiological and Ultrasound Technology
medicine.diagnostic_test
05 social sciences
Dopaminergic
fMRI
Cognition
Models
Theoretical
Magnetic Resonance Imaging
Ventral tegmental area
medicine.anatomical_structure
Neurology
nervous system
Facilitation
Neurology (clinical)
Anatomy
Functional magnetic resonance imaging
Psychology
Neuroscience
030217 neurology & neurosurgery
psychological phenomena and processes
Research Article
Zdroj: Human Brain Mapping
ISSN: 1097-0193
Popis: Motivational influences on cognitive control play an important role in shaping human behavior. Cognitive facilitation through motivators such as prospective reward or punishment is thought to depend on regions from the dopaminergic mesocortical network, primarily the ventral tegmental area (VTA), inferior frontal junction (IFJ), and anterior cingulate cortex (ACC). However, how interactions between these regions relate to motivated control remains elusive. In the present functional magnetic resonance imaging study, we used dynamic causal modeling (DCM) to investigate effective connectivity between left IFJ, ACC, and VTA in a task‐switching paradigm comprising three distinct motivational conditions (prospective monetary reward or punishment and a control condition). We found that while prospective punishment significantly facilitated switching between tasks on a behavioral level, interactions between IFJ, ACC, and VTA were characterized by modulations through prospective reward but not punishment. Our DCM results show that IFJ and VTA modulate ACC activity in parallel rather than by interaction to serve task demands in reward‐based cognitive control. Our findings further demonstrate that prospective reward and punishment differentially affect neural control mechanisms to initiate decision‐making.
Dynamic causal modeling (DCM) in functional magnetic resonance imaging data was applied to investigate effective connectivity between left IFJ, ACC, and VTA in a task‐switching paradigm comprising three distinct motivational conditions (prospective monetary reward or punishment and a control condition). Prospective punishment significantly facilitated switching between tasks on a behavioral level, while interactions between IFJ, ACC, and VTA were characterized by modulations through prospective reward. Our DCM results show that IFJ and VTA modulate ACC activity in parallel rather than by interaction to serve task demands in reward‐based cognitive control.
Databáze: OpenAIRE
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