Dynamic helical CT mammography of breast cancer

Autor: Hitoshi Fukushima, Yoji Urata, Akira Yamamoto, Sumio Mukaihara, Yoshiaki Nakamura, Taisuke Morimoto, Katsumi Hayakawa, Ryuji Okamura
Rok vydání: 2006
Předmět:
Zdroj: Radiation Medicine. 24:35-40
ISSN: 1862-5274
0288-2043
DOI: 10.1007/bf02489987
Popis: The purpose of this study was to determine whether dynamic helical computed tomography (CT)-mammography could assist in selecting the most appropriate surgical method in women with breast cancer.Preoperative contrast-enhanced helical CT scanning of the breast was performed on 133 female patients with suspicion of breast cancer at the same time as clinical, mammographic, and/or ultrasonographic examinations. The patients were scanned in the prone position with a specially designed CT-compatible device. A helical scan was made with rapid intravenous bolus injection (3 ml/s) of 100 ml of iodine contrast material. Three-dimensional maximum intensity projection (MIP) images were reconstructed, and CT findings were correlated with surgical and histopathological findings.Histopathological analysis revealed 84 malignant lesions and seven benign lesions. The sensitivity, specificity, and accuracy levels of the CT scanning were 94.6%, 58.6%, and 78.9%. Helical scanning alone revealed additional contralateral carcinomas in three of four patients and additional ipsilateral carcinomas in three of five patients. However, the technique gave false-positive readings in 24 patients. The preoperative CT-mammogram altered the surgical method in six patients.Dynamic helical CT-mammography in the prone position may be one of the choices of adjunct imaging in patients with suspected breast cancer scheduled for surgery.
Databáze: OpenAIRE
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