Audit and its impact in the management of early prostatic cancer
| Autor: | Margaret A. MclNTYRE, R. A. Elton, A. Rana, S. Christodoulou, Geoffrey D. Chisholm |
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| Rok vydání: | 1993 |
| Předmět: |
Male
medicine.medical_specialty Databases Factual Urology Audit Urology Department Hospital Hospitals University Prostate Internal medicine Epidemiology Outcome Assessment Health Care Carcinoma Medicine Humans Prospective Studies Until Disease Progression Aged Aged 80 and over Epithelioma business.industry Age Factors Cancer Prostatic Neoplasms Middle Aged medicine.disease Survival Analysis Surgery medicine.anatomical_structure Treatment Outcome Scotland business Cohort study |
| Zdroj: | British journal of urology. 71(6) |
| ISSN: | 0007-1331 |
| Popis: | An analysis was made of a prospective database of 614 men with newly diagnosed carcinoma of the prostate who presented between January 1978 and December 1990; 3-monthly updates were available on their clinical, haematological and biochemical parameters and 6-monthly updates on chest X-rays, bone scans and skeletal X-rays. It was found that 107 men (mean age 73.5 years) had early disease at presentation. Their management was based on regular surveillance and the treatment deferred until disease progression or development of symptoms. The audit of outcome measured various clinical events. Four patients (3.7%) developed local failure, 11 (10.3%) developed bone metastases, 3 (2.8%) died of cancer with a median survival of 6.3 years, and 34 (31.8%) died of intercurrent disease with a median survival of 2.6 years. The observed survival for 12 years of the whole group was similar to the expected survival for an age-matched population in Scotland. The standardised mortality ratio was 81 (95% confidence limits 57-112). |
| Databáze: | OpenAIRE |
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