Increased bone resorption and decreased bone formation in Chinese patients with hip fracture
| Autor: | Ramasamyiyer Swaminathan, C. K. Cheung, N. S. Panesar, Jean Woo, Edith M. C. Lau |
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| Rok vydání: | 1995 |
| Předmět: |
Male
China medicine.medical_specialty Endocrinology Diabetes and Metabolism Acid Phosphatase Osteocalcin Osteoporosis Poison control Parathyroid hormone Bone resorption Cohort Studies Endocrinology Calcitriol Reference Values Risk Factors Internal medicine Humans Medicine Orthopedics and Sports Medicine Bone Resorption Aged Calcifediol Aged 80 and over Hip fracture Bone Development biology Hip Fractures business.industry Acid phosphatase Middle Aged Alkaline Phosphatase medicine.disease Isoenzymes Hydroxyproline Parathyroid Hormone biology.protein Alkaline phosphatase Female business Biomarkers |
| Zdroj: | Calcified Tissue International. 56:347-349 |
| ISSN: | 1432-0827 0171-967X |
| Popis: | Biochemical markers of bone formation (bone-specific alkaline phosphatase and osteocalcin) and bone resorption (hydroxyproline excretion and bone isoenzyme of acid phosphatase) were measured in 30 patients (15 M and 15 F) with hip fracture and 30 healthy subjects matched for age and sex. Bone isoenzyme of tartrate-resistant acid phosphatase (TRACP) was measured by a recently developed specific immunoassay. Serum osteocalcin concentration and bone-specific alkaline phosphatase activity were significantly lower and serum TRACP concentration and urinary hydroxyproline excretion were elevated in patients compared with healthy subjects. We suggest that there is reduced bone formation and increased bone resorption in patients with hip fracture. |
| Databáze: | OpenAIRE |
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