Mycobacterium tuberculosis spoligotypes circulating in the Syrian population: A retrospective study
| Autor: | Monzer Hamze, Bedrossian N, Abdulkader Rahmo, Walid Karam |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Spoligotyping
Microbiology (medical) DOTS Veterinary medicine education.field_of_study medicine.medical_specialty Syria biology Epidemiology business.industry Population lcsh:QR1-502 Retrospective cohort study biology.organism_classification Virology lcsh:Microbiology Mycobacterium tuberculosis Beijing family Infectious Diseases Primary health care (PHC) M. tuberculosis Medicine education business |
| Zdroj: | International Journal of Mycobacteriology, Vol 2, Iss 3, Pp 141-147 (2013) |
| ISSN: | 2212-5531 |
| DOI: | 10.1016/j.ijmyco.2013.05.004 |
| Popis: | Objectives To characterize by spoligotyping clinical isolates of Mycobacterium tuberculosis (MTB) collected between July 2003 and October 2005 from all Syrian provinces (muhafazat). Methods All isolates ( n = 96) were cultured and identified by biochemical characteristics. DNA extracts of these samples were amplified by PCR and genotyped by spoligotyping. Results Twelve patterns were identified: 46.8% of the strains belonged to T 1 family; 20.8% to LAM 9; 10.4% to CAS; 9.3% to Haarlem 3; 4.1% to Haarlem 1; 2.1% to Family 34; and 1% to each of Family 36, EAI 5, LAM 1, LAM 8, T 3, and X 3 families. The noticeable absence of the Beijing family was not consistent with the patterns reported in most neighboring countries. Conclusion A more inclusive study of the Syrian population is necessary to more accurately identify most of the prevailing families in the country. |
| Databáze: | OpenAIRE |
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