Efficacy of Surgical Treatment of Peritoneal Carcinomatosis in Patients with Colorectal Cancer
Autor: | T. Fetsych, A P Revura |
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Jazyk: | angličtina |
Rok vydání: | 2016 |
Předmět: |
Chemotherapy
medicine.medical_specialty business.industry Colorectal cancer medicine.medical_treatment lcsh:R Significant difference lcsh:Medicine Cancer peritoneal carcinomatosis colorectal cancer medicine.disease Surgery Peritoneal carcinomatosis cytoreductive surgery Medicine In patient Surgical treatment Cytoreductive surgery business |
Zdroj: | Galician Medical Journal; Vol. 23 No. 3 (2016) Galician Medical Journal; Том 23 № 3 (2016) Galician Medical Journal; Vol 23, No 3 (2016) Galician Medical Journal, Vol 23, Iss 3 (2016) |
ISSN: | 2414-1518 2306-4285 |
Popis: | Colorectal cancer is one of the most common types of cancer in Ukraine. Prognosis for patients with peritoneal carcinomatosis is unfavorable, and life expectancy is typically less than 6 months. Cytoreductive surgery was introduced as a new method of treating these patients to prolong their survival time.The objective of the research was to evaluate and compare the efficacy of cytoreductive surgery, chemotherapy and symptomatic treatment of patients with colorectal cancer and peritoneal carcinomatosis.Materials and methods. The research included 93 patients with colorectal cancer and peritoneal carcinomatosis. All patients were divided into 3 groups depending on the method of treatment being used after the detection of peritoneal carcinomatosis: Group I - cytoreductive surgery, Group II - palliative chemotherapy, Group III - symptomatic treatment. Cumulative overall survival in three groups was analyzed using the Kaplan-Meier method.Results. Statistically significant difference in overall survival was observed between patients treated with different methods. The median overall survival of patients of Group I (n=44) was 15.5 months; the median overall survival of patients of Group II (n=27) was 5.9 months; in patients of Group III (n=22) it was 3.1 months (p |
Databáze: | OpenAIRE |
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