17.ALPHA.-Hydroxylase Deficiency Accompanied by Adrenal Myelolipoma
| Autor: | Masatomo Mori, Manabu Honma, Makoto Imamura, Masami Murakami, Takashi Nagai |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Myelolipoma
medicine.medical_specialty medicine.drug_class Adrenal Gland Neoplasms Adrenocorticotropic hormone Plasma renin activity chemistry.chemical_compound Corticosterone Internal medicine Internal Medicine medicine Humans Adrenal Hyperplasia Congenital business.industry 17-alpha-Hydroxyprogesterone Incidentaloma General Medicine Middle Aged medicine.disease Androgen Magnetic Resonance Imaging Hormones Hypokalemia Treatment Outcome Endocrinology chemistry Female medicine.symptom business Hormone |
| Zdroj: | Internal Medicine. 40:920-923 |
| ISSN: | 1349-7235 0918-2918 |
| DOI: | 10.2169/internalmedicine.40.920 |
| Popis: | A 45-year-old woman was admitted because of hypertension and hypokalemia. Primary amenorrhea from birth was noted. Plasma renin activity (PRA), 17α-hydroxyprogesterone and androgen levels were low, but progesterone, 11-deoxycorticosterone, corticosterone and adrenocorticotropic hormone (ACTH) were elevated, resulting in a diagnosis of 17α-hydroxylase deficiency. Abdominal magnetic resonance imaging revealed a round mass in the left adrenal region, the specimen of which was diagnosed as myelolipoma. After removal of the tumor, the blood pressure, serum potassium and hormone levels were unchanged, indicating an adrenal non-functioning tumor. Excessive ACTH secretion over a long period may stimulate the development of adrenal myelolipoma.(Internal Medicine 40: 920-923, 2001) |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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