Acute hemarthrosis: A histological, biochemical, and biomechanical correlation of early effects on the anterior cruciate ligament in a rabbit model
| Autor: | Kenneth K. Ishizue, Roger Lyon, David Amiel, Savio L. C. Woo |
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| Rok vydání: | 1990 |
| Předmět: |
Male
medicine.medical_specialty Knee Joint Anterior cruciate ligament Iron deposition Autologous blood Hemarthrosis medicine Animals Orthopedics and Sports Medicine Lagomorpha biology business.industry musculoskeletal neural and ocular physiology Biomechanics musculoskeletal system medicine.disease biology.organism_classification Biomechanical Phenomena Surgery Disease Models Animal Microbial Collagenase surgical procedures operative medicine.anatomical_structure Anesthesia Acute Disease Ligaments Articular Rabbit model Collagenase Collagen Rabbits business human activities medicine.drug |
| Zdroj: | Journal of Orthopaedic Research. 8:548-554 |
| ISSN: | 1554-527X 0736-0266 |
| DOI: | 10.1002/jor.1100080411 |
| Popis: | The early histological, biochemical, and biomechanical characteristics of the anterior cruciate ligament (ACL) were determined in a rabbit model of acute hemarthrosis. The ACLs of 19 rabbits were given seven consecutive daily knee injections of 2 ml of fresh autologous blood, and then compared to contralateral ACLs from control knees injected with 2 ml of lactated Ringer's solution daily for 7 days. The rabbits were then sacrificed. Synovial proliferation with iron deposition within synoviocytes was observed; however, the architecture of the ACL was maintained. Additionally, the total collagen content, collagenase activity, and biomechanical properties of the ACL were unaltered. |
| Databáze: | OpenAIRE |
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