Compliance with inhaled therapy and morbidity from asthma
| Autor: | T. J. H. Clark, G. M. Cochrane, C.R. Horn |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Pulmonary and Respiratory Medicine
Adult Male medicine.drug_class medicine.medical_treatment Peak Expiratory Flow Rate Urine Bronchodilator Forced Expiratory Volume Administration Inhalation medicine Humans Albuterol Prospective cohort study Asthma Chemotherapy Inhalation business.industry Respiratory disease Beclomethasone medicine.disease respiratory tract diseases Anesthesia Salbutamol Patient Compliance Female business medicine.drug |
| Zdroj: | Respiratory medicine. 84(1) |
| ISSN: | 0954-6111 |
| Popis: | Patient compliance with a standardized incremental regime of inhaled anti-asthma therapy has been assessed in alarge, prospective study in general practice. Urine salbutamol estimations were made in 30 patients who had the largest improvement with therapy (mean increase in FEV 1 0·451 above baseline: Responsive) and in 30 patients whose airflow obstruction failed to improve (FEV 1 -0·141: Nonresponsive). The urine salbutamol concentrations rose over the 9 month period in the responsive patients as expected with the incremental doses prescribed, and were significantly higher than urine levels in nonresponsive patients at two dose levels. Poor compliance with prescribed inhaled therapy is an important cause of persistent morbidity from asthma. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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