Vitamin requirements in patients receiving total parenteral nutrition
| Autor: | George E. Nichoalds, H. C. Meng, Michael D. Caldwell |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Vitamin
Adult medicine.medical_specialty Parenteral Nutrition Riboflavin chemistry.chemical_compound Folic Acid Postoperative Complications Medicine Humans In patient Nutritional Physiological Phenomena Postoperative Care Vitamin C Dose-Response Relationship Drug business.industry Nutritional Requirements Liter Vitamins Ascorbic acid Surgery Dose–response relationship Parenteral nutrition chemistry Parenteral Nutrition Total business |
| Zdroj: | Archives of surgery (Chicago, Ill. : 1960). 112(9) |
| ISSN: | 0004-0010 |
| Popis: | • This study represents an initial attempt to define intravenous vitamin requirements in adult patients receiving total parenteral nutrition (TPN). We have investigated two different vitamin formulations for their ability to maintain normal circulating blood levels of vitamins A, C, E, B 12 , folic acid, and riboflavin. Administration of 1.1 ml of Multi-Vitamin Infusion (MVI) solution supplemented with 100 μg of folic acid, 10 μg of vitamin B 12 , and 100 mg of vitamin C, per liter of TPN infusate (patients received an average of about 3 liters/day), maintained normal or higher than normal levels of vitamins C, B 12 , and riboflavin, but resulted in less-than-normal levels of vitamins A, E, and folic acid. Increasing the amount of MVI to 1.4 ml and the folic acid to 200 μg, and decreasing the ascorbic acid to 70 mg and vitamin B 12 to 5 μg/liter of TPN infusate, resulted in normal blood levels of all tested vitamins within two weeks after initiating TPN therapy, and normal blood levels were then maintained at this dosage for additional periods of time up to three weeks. ( Arch Surg 112:1061-1064, 1977) |
| Databáze: | OpenAIRE |
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