Short report: Schistosoma mansoni miracidia are killed by the defense system of an Argentine strain of Biomphalaria straminea
| Autor: | S. M. Gonzalez Cappa, M Torr es Jordá, Z Andrade, L Grassi |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Biomphalaria straminea
Argentina Biomphalaria Snail Disease Vectors Pulmonata Host-Parasite Interactions Microbiology Mice Virology biology.animal parasitic diseases Gastropoda Animals Biomphalaria glabrata Parasite Egg Count biology fungi Schistosoma mansoni Anatomy biology.organism_classification Schistosomiasis mansoni Infectious Diseases Parasitology Disease Susceptibility Trematoda |
| Zdroj: | The American Journal of Tropical Medicine and Hygiene. 65:290-292 |
| ISSN: | 1476-1645 0002-9637 |
| Popis: | Biomphalaria straminea snails from Argentina fail to shed cercariae even if exposed to high doses of Schistosoma mansoni EC miracidia. Alternative explanations for this failure are that miracidia are unable to penetrate the snail's epithelium or that the miracidia are killed by the snail's defense system. To discriminate between these 2 possibilities, B. straminea snails were individually exposed to increasing doses of miracidia. Susceptible B. glabrata were used as controls. Exposed snails were fixed 12 hr after exposure, and histological sections of the whole specimens were examined. Miracidia were seen to penetrate the epithelium of B. straminea and B. glabrata at similar rates (14.7%), independent of the exposure level. Regardless of the miracidial dose, 94% of the penetrating miracidia appeared encapsulated by the B. straminea defense system, whereas in B. glabrata, only 42% of the miracidia underwent encapsulation. These results show that resistance of B. straminea to S. mansoni EC strain is due to an efficient defense system that destroys miracidia once they have penetrated. |
| Databáze: | OpenAIRE |
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