Comparing mail-in self-collected specimens sent via United States Postal Service versus clinic-collected specimens for the detection of Chlamydia trachomatis and Neisseria gonorrhoeae in extra-genital sites
| Autor: | Claire C. Bristow, Katheryn R. Salow, Jeffrey D. Klausner, Mark R. McGrath, Adam Carl Cohen |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Male
0301 basic medicine lcsh:Medicine Chlamydia trachomatis Pathology and Laboratory Medicine medicine.disease_cause Geographical locations Men who have sex with men film.subject 0302 clinical medicine Medicine and Health Sciences Medicine 030212 general & internal medicine Chlamydia lcsh:Science Multidisciplinary Obstetrics Clinical Laboratory Sciences Bacterial Pathogens 3. Good health Clinical Laboratories Infectious Diseases Medical Microbiology Anatomy Pathogens Neisseria Research Article medicine.medical_specialty Patients Free clinic Concordance 030106 microbiology Sexually Transmitted Diseases Men WHO Have Sex with Men Convenience sample Microbiology Specimen Handling 03 medical and health sciences Diagnostic Medicine Postal service Humans Sex organ Postal Service Homosexuality Male Microbial Pathogens Gynecology Bacteria business.industry lcsh:R Rectum Organisms Biology and Life Sciences Neisseria gonorrhoeae United States Gastrointestinal Tract Health Care film People and Places North America Pharynx Population Groupings lcsh:Q business Digestive System Sexuality Groupings |
| Zdroj: | PLoS ONE, Vol 12, Iss 12, p e0189515 (2017) PLoS ONE |
| ISSN: | 1932-6203 |
| Popis: | Objectives To evaluate the concordance between clinic-collected extra-genital specimens and self-collected mailed-in extra-genital specimens among participants seeking sexually transmitted infection testing at a free clinic in Hollywood, CA. Methods A convenience sample of 210 men who have sex with men were enrolled between February 29, 2016 and December 21, 2016 and received mail-in testing kits for Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG). All testing was performed using the GeneXpert® CT/NG (Cepheid, Sunnyvale, CA). Results From the 210 mail-in kits distributed, 149 mail-in kits (71.0%) were returned to the laboratory, resulting in 145 pairs (clinic-collected and mail-in) of rectal test results and 148 pairs of pharyngeal test results for both CT and NG detection. The concordance was 95.0% for all CT rectal tests, 99.3% for all CT pharyngeal tests, 95.7% for all NG rectal tests, and 97.2% for all NG pharyngeal tests. Conclusion Roughly two-thirds of mail-in test kits were returned and concordance was generally high, however more than one-third of positive results were missed in mail-in samples. The prevalence of potential false-negative results among mail-in samples warrants caution when implementing mail-in STI testing strategies. |
| Databáze: | OpenAIRE |
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