Use of Serology to Diagnose Pneumonia Caused by Nonencapsulated Haemophilus influenzae and Moraxella catarrhalis
| Autor: | Birger Trollfors, Lars Å. Burman, Maija Leinonen |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Adult
Male Haemophilus Infections Neisseriaceae Infections Enzyme-Linked Immunosorbent Assay medicine.disease_cause Microbiology Haemophilus influenzae Serology Moraxella catarrhalis Moraxella (Branhamella) catarrhalis medicine Humans Immunology and Allergy Serologic Tests Moraxella Bacterial Capsules biology Pneumonia biology.organism_classification medicine.disease Antibodies Bacterial Infectious Diseases Branhamella Immunology Sputum Female medicine.symptom |
| Zdroj: | Journal of Infectious Diseases. 170:220-222 |
| ISSN: | 1537-6613 0022-1899 |
| DOI: | 10.1093/infdis/170.1.220 |
| Popis: | Antibodies against nonencapsulated Haemophilus influenzae and Moraxella (Branhamella) catarrhalis were measured by ELISA in paired sera from 158 adult patients with pneumonia. A mixture of 10 clinical isolates of each species was used as antigen. Eleven patients (7%) showed significant increases in antibody to H. influenzae. In 3 of them, the organism was isolated from transtracheal aspirate and in another 7 from sputum, nasopharynx, or both. Six patients with nonencapsulated H. influenzae in transtracheal aspirate cultures did not show any antibody increase. Six patients had significant increases in antibody to M. catarrhalis. The organism was isolated in transtracheal aspirates from 1 of them and in sputum and nasopharynx (or both) from another 3. Two patients with M. catarrhalis in transtracheal aspirate cultures showed no antibody response. In conclusion, the serologic methods increased the possibility to diagnose infections caused by the two agents but had low sensitivity. |
| Databáze: | OpenAIRE |
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