Serum Cystatin C as a Predictor of Acute Kidney Transplant Rejection

Autor: Biochemistry. Nephrology, Fadhil B. Shamkhi, Ala Sh. Ali, Hedef D. El-Yassin
Rok vydání: 2015
Předmět:
Zdroj: مجلة كلية الطب, Vol 57, Iss 3 (2015)
ISSN: 2410-8057
0041-9419
DOI: 10.32007/med.1936/jfacmedbagdad.v57i3.2
Popis: Background: Accurate and rapid assessment of allograft function is essential. Cystatin C has recently been proposed as an alternative marker of glomerular filtration rate (GFR). Its diagnostic value for the longitudinal assessment of graft function has not been addressed well.Objective: To study the validity of cystatin C as an early marker and predictor of acute transplant rejection in the first week post transplantation.Subjects and Methods: Sixty six renal transplants recipients recruited. The study conducted in four renal transplantation centers in Baghdad for the period from September to December 2011. Serum creatinine and cystatin C concentrations measured 48 hours before transplantation and day 3 and 7 post transplantation.Results: Serum Cystatin C observed to significantly increased at day 3 (p
Databáze: OpenAIRE