Crystal-Associated Colitis with Ulceration Leading to Hematochezia and Abdominal Pain
| Autor: | Aaron Reiprich, Abraham Mathew, John M. Levenick, Meeta Desai, Zhaohai Yang, Nancy Khov |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Abdominal pain
medicine.medical_specialty Crystal deposition Radiation Colitis Case Report Sevelamer Disease Hematochezia Gastroenterology 03 medical and health sciences 0302 clinical medicine Internal medicine Carcinoma medicine Medical history Ulceration lcsh:RC799-869 Colitis Cholestyramine Hepatology business.industry medicine.disease Surgery 030220 oncology & carcinogenesis lcsh:Diseases of the digestive system. Gastroenterology 030211 gastroenterology & hepatology medicine.symptom business medicine.drug |
| Zdroj: | Case Reports in Gastroenterology Case Reports in Gastroenterology, Vol 10, Iss 2, Pp 332-337 (2016) |
| ISSN: | 1662-0631 |
| Popis: | Lower GI bleeding is a common cause for hospitalization in adults. Medication-associated mucosal injury is an important clinical entity that can result in significant morbidity and mortality. We present the case of a 45-year-old woman with a 3-month history of intermittent abdominal cramping and rectal bleeding. Her medical history was extensive and included end-stage renal disease and a remote history of endometrial carcinoma that was treated with radiation. Initial workup was concerning for ischemic and radiation colitis, however, histology was most consistent with acute inflammation and ulceration associated with crystal fragments. Sevelamer and cholestyramine are commonly used ion-exchange resins that have been associated with mucosal damage. Both medications were discontinued and her symptoms resolved. Our case highlights an underrecognized but important cause of hematochezia. |
| Databáze: | OpenAIRE |
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