High prevalence of dyslipidemia and associated risk factors among rural Chinese adults
Autor: | Liang Guo, Zhao Li, Yingxian Sun, Guozhe Sun, Ying Zhou, Hongmei Yang |
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Jazyk: | angličtina |
Předmět: |
Adult
Male Rural Population Gerontology China medicine.medical_specialty Endocrinology Diabetes and Metabolism Population Clinical Biochemistry Age Distribution Endocrinology Environmental health Epidemiology Prevalence Humans Medicine Risk factor education National Cholesterol Education Program Triglycerides Aged Dyslipidemias Biochemistry medical education.field_of_study business.industry Research Cholesterol HDL Biochemistry (medical) Cholesterol LDL Middle Aged medicine.disease Obesity Dyslipidemia Risk factors Rural China Population study Marital status Female business |
Zdroj: | Lipids in Health and Disease |
ISSN: | 1476-511X |
DOI: | 10.1186/1476-511x-13-189 |
Popis: | Background Dyslipidemia is a key independent modifiable risk factor for Cardiovascular Disease, which is a leading contributor to morbidity and mortality in most developed and developing countries. This study was designed to investigate the current epidemiological features of dyslipidemia among adults in rural China. Methods Between January 2013 and August 2013, we conducted a cross-sectional study involving 11,956 subjects with age ≥35 years in a general Chinese population. Permanent residents of the population were invited to participate in the study and the response rate was at 85.3%. Dyslipidemia was identified based on serum lipids levels following the standards proposed by the National Cholesterol Education Program Adult Treatment Panel III. Multivariate logistic regression analysis was used to evaluate the associated risk factors for dyslipidemia. Results Within the study population, 16.4% had high TC, 13.8% had low HDL-C, 7.6% had high LDL-C, and 17.3% had high TG concentrations. Prevalence of lipid abnormality (including borderline dyslipidemia and dyslipidemia) was 47.8%, 13.8%, 25.7% and 30.7% for TC, HDL-C, LDL-C and TG, respectively. Detailed analysis indicated that 36.9% of this population had at least one type of dyslipidemia and 64.4% had at least one type of abnormal lipid concentration. Thus, this study observed an alarmingly higher prevalence of lipid abnormality, in a relatively large population, compared to previous studies. Further, we determined that not all of the risk factors studied, including age, gender, hypertension, diabetes mellitus, obesity, smoking, drinking, education level, marital status, and family income, influenced dyslipidemia to the same extent. Conclusions Our present study, in a population of 11,956 adults in Liaoning Providence, demonstrated a very high prevalence of dyslipidemia, which represented an alarming rise since the publication of our previous study and other similar studies around the world, which report lower levels. We also examined various risk factors for dyslipidemia, many of which are modifiable risk factors for Cardiovascular Disease (CVD), to provide a comprehensive view that will help in designing strategies to slow the rapid spread and promote effective measures to treat dyslipidemia. Our ultimate goal is to prevent the increasing prevalence of lipid abnormality and reduce the burden of CVD in rural China. |
Databáze: | OpenAIRE |
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