Differences in the Incidence of Pathologic Lesions on the Oral Mucosa in Patients Undergoing Hemodialysis vs Renal Organ Transplant Recipients Subjected to Long-term Pharmacologic Immunosuppressive Therapy
| Autor: | Magdalena Durlik, Piotr Wychowański, Mirosław Grzeszczyk, Martyna Osiak, Piotr Fiedor |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Gastroenterology Pallor Organ transplantation Postoperative Complications Renal Dialysis Internal medicine medicine Humans Oral mucosa Leukoplakia Immunosuppression Therapy Periodontitis Transplantation business.industry Incidence Mouth Mucosa Immunosuppression Middle Aged medicine.disease Kidney Transplantation Dysgeusia medicine.anatomical_structure Kidney Failure Chronic Female Surgery Hemodialysis medicine.symptom Mouth Diseases business Immunosuppressive Agents |
| Zdroj: | Transplantation Proceedings. 52:2409-2411 |
| ISSN: | 0041-1345 |
| DOI: | 10.1016/j.transproceed.2020.02.105 |
| Popis: | Disorders of homeostasis and an increased incidence of infection in patients undergoing hemodialysis causes frequent appearance of pathologic changes in the oral mucosa. The organ transplant and subsequent pharmacologic immunosuppression may result in systemic disorders manifesting by pathologic oral lesions. Methods The study was conducted on 18 patients undergoing hemodialysis and 18 patients after renal transplant. The study comprised case taking and physical examination, including detailed intraoral and extraoral examination. Results The intraoral examination revealed gingivitis in 61.1% of patients in both groups. In the renal transplant group compared with the hemodialysis group 55.6% vs 38.9% of patients had gingival recession, 55.6% vs 44.4% had periodontitis, 27.8% vs 22.2% had macroglossia, and 11.1% vs 5.6% had geographic tongue, respectively. In the patients on hemodialysis leukoplakia and pallor or pathologic pigmentation of oral mucosa were more frequently observed lesions. Other significant findings in the renal transplant group were lingual papillary atrophy, aphthae, and erythroplakia. Patients of both group reported xerostomia, halitosis, gum bleeding, dysgeusia in their history. Discussion Both groups of patients after renal transplant and patients undergoing hemodialysis presented pathologic lesions in the oral cavity. The study revealed the differences between type and frequency of these pathologic changes, which shows different effect of the above methods of treatment of end-stage renal failure on the oral cavity. |
| Databáze: | OpenAIRE |
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