DYNAMICS OF CLINICAL AND BIOCHEMICAL PARAMETERS AND FUNCTIONAL STATE OF THE AUTONOMIC NERVOUS SYSTEM IN PATIENTS WITH ACUTE HEPATITIS B WITH CHRONIC ALCOHOL USE IN HEPATOTOXIC DOSES
| Autor: | V. G. Savelyev, O. V. Ryabokon, О. P. Mashko, O. O. Furyk, T. E. Onishenko |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Pathology business.industry Convalescence media_common.quotation_subject use alcohol in hepatotoxic doses lcsh:R heart rate variability lcsh:Medicine Hepatitis B medicine.disease Gastroenterology Pathogenesis Autonomic nervous system acute hepatitis В Internal medicine Vagotonia medicine Etiology Heart rate variability Itching medicine.symptom business media_common |
| Zdroj: | Zaporožskij Medicinskij Žurnal, Iss 1, Pp 60-63 (2014) |
| ISSN: | 2310-1210 2306-4145 |
| Popis: | Relevance of hepatitis B due to the high incidence complexity of pathogenesis, ineffective treatment, severe consequences of the disease. Among combined lesions of the liver, special attention is paid to viral-alcoholic type. One of the mechanisms of chronic hepatitis of different etiology is violation of the functional activity of the autonomic nervous system. The aim of this work- to determine the dynamics of spectral indices of heart rate variability in patients with acute hepatitis B from chronic use of alcohol in hepatotoxic doses. Materials and methods. 133 patients with acute hepatitis B were under observation. Patients were divided into groups taking account the presence or absence of chronic use of alcohol in hepatotoxic doses and using the classification of alcohol consumption based on the frequency and dose of consumed alcohol. I group comprised 52 patients with chronic use of alcohol in the hepatotoxic doses, II group consisted of 81 patient without this factor. Heart rate variability was diagnosed using computer cardiointervalometry performed by electrocardiographic diagnostic system CardioLab-2000. 20 healthy individuals were in the control group. Results and discussion. Prodromal period in patients of the I group was longer (p0,05). However, only patients in group I had marked hemorrhagic manifestations (5,8 %) and itching (7.7%). Average serum total bilirubin level was higher (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|