| Autor: |
Dufresne, Sébastien, Boulanger-Piette, Antoine, Bossé, Sabrina, Anteneh Argaw, Dounia Hamoudi, Marcadet, Laetitia, Gamu, Daniel, Fajardo, Val, Yagita, Hideo, Penninger, Josef, A. Russell Tupling, Frenette, Jérôme |
| Rok vydání: |
2018 |
| Předmět: |
|
| DOI: |
10.6084/m9.figshare.6193616.v1 |
| Popis: |
Table 1. All treatments and muscle-specific genetic deletion of RANK did not have an impact on muscle mass at 5 weeks of age. Table 2. Primers used for PCR amplification and genotyping. Figure 1. RANK deletion reduces EDL muscle damage in 5 week-old mdx mice. Figure 2. Full-length OPG-Fc treatment and RANK deletion protect dystrophic skeletal muscles. Figure 3. RANK deletion protects skeletal muscles in old mdx mice. Figure 4. Full-length OPG-Fc mitigates muscular dystrophy in fast-twitch skeletal muscles. Figure 5. Recovery scores of various key functional parameters of skeletal muscles evaluated ex vivo from dystrophic mice treated with full-length OPG-Fc, anti-RANKL, anti-TRAIL and/or selectively deficient in muscle RANK. Figure 6. Full-length OPG-Fc markedly increases functional performance during eccentric downhill running. Figure 7. Recovery scores of forced and voluntary physical exercise performance in full-length OPG-Fc treated dystrophic mdx mice. Figure 8. Muscle RANK deletion and full-length OPG-Fc treatment did not increase SERCA activity in dystrophic Sol and Dia muscles. (DOCX 3505 kb) |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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