Reductive Radical Cascades Triggered by Alkoxyl Radicals in the β-Cyclodextrin Framework

Autor:	Angeles Martín, Ernesto Suárez, Elisa I. León, Inés Pérez-Martín
Přispěvatelé:	Fundación CajaCanarias, Gobierno de Canarias, Ministerio de Economía y Competitividad (España)
Rok vydání:	2018
Předmět:	chemistry.chemical_classification Cyclodextrin 010405 organic chemistry Organic Chemistry 010402 general chemistry Photochemistry 01 natural sciences Biochemistry 0104 chemical sciences Reductive radical cascades chemistry Alkoxyl radicals Physical and Theoretical Chemistry
Zdroj:	Digital.CSIC. Repositorio Institucional del CSIC instname
ISSN:	1523-7052
Popis:	The generation and fate of 2,3,6-icosa-O-methyl-β-cyclomaltoheptaos-6-O-yl radical under reductive conditions is described. Two radical cascade reactions are involved: the main one is triggered by a 1,8-HAT of the hydrogen at 5C. The radical can reach the anomeric hydrogen at 1C three sugar units ahead using a six-step sequence. The different hydrogen donor ability of the group 14 hydrides permits one to selectively stop the cascade at 5C, 2C, and 4C to obtain β-CD with a β-l-Idop unit, acyclic hepta-, and hexa-saccharide structures, respectively. Financial support by the Investigation Programs of theMinisterio de Economía y Competitividad (No. CTQ2010-18244), Fundación CajaCanarias (No. 2015-BIO08) and the Gobierno de Canarias (No. ProID2017010017) is acknowledged.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c671729e591b9b799765cd1842aaa2c https://pubmed.ncbi.nlm.nih.gov/29767983 Zobrazit plný text záznamu