Obstructive uropathy as the only manifestation of flare in a patient with systemic lupus erythematosus and anti-phospholipid syndrome
| Autor: | Cristina Drenkard, G. Martellotto, S. Gamróm, R. Belén, S. Asia, A. Maria Sesín |
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| Rok vydání: | 2008 |
| Předmět: |
medicine.medical_specialty
Pathology Meatus Urinary Bladder Cystitis Interstitial Hydronephrosis urologic and male genital diseases Gastroenterology Fatal Outcome Rheumatology Lower urinary tract symptoms Internal medicine medicine Humans Lupus Erythematosus Systemic skin and connective tissue diseases Obstructive uropathy Mucous Membrane Lupus erythematosus Urinary bladder business.industry Urography Middle Aged Antiphospholipid Syndrome medicine.disease Combined Modality Therapy medicine.anatomical_structure Patient Compliance Female Ureter Chronic Inflammatory Infiltrate business Ureteral Obstruction Anti-SSA/Ro autoantibodies Pyelogram |
| Zdroj: | Lupus. 17:46-49 |
| ISSN: | 1477-0962 0961-2033 |
| DOI: | 10.1177/0961203307084711 |
| Popis: | Chronic interstitial cystitis and ureteral stenosis has occasionally been reported in systemic lupus erythematosus, mostly associated with gastrointestinal symptoms. We report a case of obstructive uropathy associated to chronic interstitial cystitis as the only manifestation of lupus flare in a patient with SLE and anti-phospholipid syndrome (APS) who had been in remission for many years. The development of chronic interstitial cystitis in patients with SLE and APS has not been previously reported. Histopathological study of her urinary bladder and ureteral meatus showed chronic inflammatory infiltrate in the subepithelium. Lack of significant lower urinary tract symptoms and gastrointestinal involvement were some of the factors that could have prevented an earlier diagnosis. Obstructive uropathy and renal insufficiency initially improved with immunosuppressive treatment and endoureteral protheses, but poor compliance to the therapy led to ominous ending. |
| Databáze: | OpenAIRE |
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