Detection of novel sequences related to african Swine Fever virus in human serum and sewage
| Autor: | James M. Pipas, Stacy R. Finkbeiner, Rachel M. Presti, Herbert W. Virgin, Guoyan Zhao, Lori R. Holtz, Lindsay Droit, Joy Loh, Zoilmar Villasana, Rosina Girones, David Q.-H. Wang, Byron Calgua, Collin Todd |
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| Rok vydání: | 2009 |
| Předmět: |
Serum
Genetic diversity biology Sewage business.industry Immunology Molecular Sequence Data Outbreak biology.organism_classification Microbiology African swine fever virus Virology African Swine Fever Virus Virus Blood serum Genetic Diversity and Evolution Phylogenetics Insect Science Humans Amino Acid Sequence business Virus classification Phylogeny |
| Zdroj: | Journal of virology. 83(24) |
| ISSN: | 1098-5514 |
| Popis: | The family Asfarviridae contains only a single virus species, African swine fever virus (ASFV). ASFV is a viral agent with significant economic impact due to its devastating effects on populations of domesticated pigs during outbreaks but has not been reported to infect humans. We report here the discovery of novel viral sequences in human serum and sewage which are clearly related to the asfarvirus family but highly divergent from ASFV. Detection of these sequences suggests that greater genetic diversity may exist among asfarviruses than previously thought and raises the possibility that human infection by asfarviruses may occur. |
| Databáze: | OpenAIRE |
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