Association of Allogeneic Blood Transfusions and Long-Term Survival of Patients with Gastric Cancer after Curative Gastrectomy
| Autor: | Masaki Nakamura, Teiji Naka, Toshiyasu Ojima, Mikihito Nakamori, Keiji Hayata, Masahiro Katsuda, Hiroki Yamaue, Makoto Iwahashi, Takeshi Iida |
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| Rok vydání: | 2009 |
| Předmět: |
Male
Oncology medicine.medical_specialty Blood transfusion Anemia medicine.medical_treatment Blood Loss Surgical Logistic regression Gastroenterology Gastrectomy Stomach Neoplasms Internal medicine medicine Humans Blood Transfusion Survival analysis Aged business.industry Hazard ratio Cancer Retrospective cohort study Perioperative Middle Aged Prognosis medicine.disease Survival Analysis Female Surgery business |
| Zdroj: | Journal of Gastrointestinal Surgery. 13:1821-1830 |
| ISSN: | 1873-4626 1091-255X |
| Popis: | The relationship between perioperative allogeneic blood transfusions and poor prognosis in patients with gastric cancer remains controversial. The aim of this study is to examine the effect of perioperative blood transfusions on long-term survival of patients undergoing curative gastric resection for gastric cancer. Eight hundred fifty-six consecutive patients with gastric cancer who underwent curative gastrectomy (R0) from January 1, 1991 through December 31, 2002 were enrolled in this retrospective study. A multivariate overall survival analysis using Cox proportional hazard regression model revealed macroscopically infiltrative tumor, tumor infiltration of serosa, lymph node metastasis, blood transfusions (hazard ratio, 2.69), pulmonary disease, and liver dysfunction as prognostic factors for long-term survival. Blood transfusion was an independent prognostic factor at all stages of disease. Disease-specific and overall survival showed significant differences between the transfused and nontransfused groups (log-rank, P |
| Databáze: | OpenAIRE |
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