Novel 3D heart left ventricle muscle segmentation method for PET-gated protocol and its verification
| Autor: | K. Kaluzynski, Roberto Sciagrà, Paola Saletti, Rita Bonini, Cyrill Burger, Elena Lorenzini, Tomasz Kubik, Selene Margiacchi, Alessandro Passeri |
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| Rok vydání: | 2019 |
| Předmět: |
Heart Ventricles
Cardiac-Gated Imaging Techniques Bending Imaging phantom 030218 nuclear medicine & medical imaging 03 medical and health sciences Imaging Three-Dimensional 0302 clinical medicine Tensile Strength medicine Humans Radiology Nuclear Medicine and imaging Segmentation University medical Volume quantification left ventricle cardiology Protocol (science) Phantoms Imaging business.industry Myocardium General Medicine Biomechanical Phenomena Segmentation method Model method medicine.anatomical_structure Gated PET imaging Ventricle Positron-Emission Tomography 030220 oncology & carcinogenesis Original Article business Algorithm Algorithms Software Volume (compression) |
| Zdroj: | Annals of Nuclear Medicine |
| ISSN: | 1864-6433 0914-7187 |
| Popis: | Objective The aim of this study was to propose and verify a universal method of left ventricular myocardium segmentation, able to operate on heart gated PET data with different sizes, shapes and uptake distributions. The proposed method can be classified as active model method and is based on the BEAS (B-spline Explicit Active Surface) algorithm published by Barbosa et al. The method was implemented within the Pmod PCARD software package. Method verification by comparison with reference software and phantom data is also presented in the paper. Methods The proposed method extends the BEAS model by defining mechanical features of the model: tensile strength and bending resistance. Formulas describing model internal energy increase during its stretching and bending are proposed. The segmentation model was applied to the data of 60 patients, who had undergone cardiac gated PET scanning. QGS by Cedars-Sinai and ECTb by Emory University Medical Centre served as reference software for comparing ventricular volumes. The method was also verified using data of left ventricular phantoms of known volume. Results The results of the proposed method are well correlated with the results of QGS (slope: 0.841, intercept: 0.944 ml, R2: 0.867) and ECTb (slope: 0.830, intercept: 2.109 ml, R2: 0.845). The volumes calculated by the proposed method were very close to the true cavity volumes of two different phantoms. Conclusions The analysis of gated PET data by the proposed method results in volume measurements comparable to established methods. Phantom experiments demonstrate that the volume values correspond to the physical ones. |
| Databáze: | OpenAIRE |
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