Olanexidine gluconate formulations as environmental disinfectants for enveloped viruses infection control
| Autor: | Kaoru Imai, Daisuke Sano, Sachi Yamagawa, Akifumi Hagi |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Microbiology (medical)
2019-20 coronavirus outbreak medicine.drug_class Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Disinfectant Biguanides Glucuronates Microbial Sensitivity Tests 030501 epidemiology Cell Line Microbiology 03 medical and health sciences Viral envelope Antiseptic Olanexidine gluconate Environmental Microbiology Humans Infection control Medicine Infection Control 0303 health sciences 030306 microbiology business.industry General Medicine Disinfection Infectious Diseases Rs virus Viral Envelope Viruses 0305 other medical science business Disinfectants |
| Zdroj: | Journal of Hospital Infection. 112:37-41 |
| ISSN: | 0195-6701 |
| Popis: | This study investigated the potential of olanexidine gluconate as environmental disinfectant against enveloped viruses in the suspension test and three non-porous surface tests. In the suspension test, olanexidine gluconate showed immediate virucidal activity. In addition, non-porous surface tests demonstrated that, although the immediate effect of aqueous formulations was weak, the final virucidal efficacy outcompeted that of ethanol for disinfection. Furthermore, the effectiveness of olanexidine gluconate persisted even after drying on environmental surfaces. This study demonstrated the potential usage of olanexidine gluconate formulations as an environmental disinfectant in the infection control of enveloped viruses. |
| Databáze: | OpenAIRE |
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