Multiple Synchronous Sporadic Gastrointestinal Stromal Tumors in the Stomach and Jejunum
| Autor: | Sohachi Nanjo, Shozo Hojo, Hiroaki Takagi, Shinya Kajiura, Saito Kobayashi, Haruka Fujinami, Mami Tokunaga, Tomoyuki Okumura, Hiroki Yoshita, Tohru Watanabe, Hiroshi Mihara, Momoko Akashi, Yoko Ishii, Toshiro Sugiyama, Takayuki Ando, Isaya Hashimoto |
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| Rok vydání: | 2018 |
| Předmět: |
Male
0301 basic medicine Gastrointestinal bleeding Pathology medicine.medical_specialty Stromal cell Gastrointestinal Stromal Tumors Case Report Jejunum Jejunal Neoplasm 03 medical and health sciences 0302 clinical medicine Stomach Neoplasms Melena Internal Medicine medicine Humans Aged Jejunal Neoplasms medicine.diagnostic_test business.industry Stomach digestive oral and skin physiology Histology General Medicine medicine.disease digestive system diseases Endoscopy Proto-Oncogene Proteins c-kit 030104 developmental biology medicine.anatomical_structure 030220 oncology & carcinogenesis multiple GISTs medicine.symptom Tomography X-Ray Computed c-kit mutation business |
| Zdroj: | Internal Medicine |
| ISSN: | 1349-7235 0918-2918 |
| DOI: | 10.2169/internalmedicine.0229-17 |
| Popis: | A 77-year-old patient was admitted to our hospital for the further examination of melena. A computed tomography scan detected two submucosal tumors (SMTs) in the stomach and jejunum. Double-balloon endoscopy revealed the presence of a delle on the jejunal SMT, suggesting that the SMT was the origin of the gastrointestinal bleeding. Both tumors were surgically resected and subsequently diagnosed via histology as gastrointestinal stromal tumors (GISTs). Furthermore, the two GISTs had different mutations in the c-kit gene, suggesting that they were derived from different clonal origins. This report depicts an extremely rare case of multiple synchronous sporadic GISTs in the stomach and jejunum. |
| Databáze: | OpenAIRE |
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