Whole-Body 99mTc-Octreotide Scintigraphy With SPECT/CT to Detect Occult Tumor Inducing Paraneoplastic Osteomalacia
| Autor: | Maurício Etchebehere, Elaine Maria Ingrid Amstalden, Fabio Payao Pereira, Wilson André Ichiki, Elba Cristina de Sa Etchebehere, Napoleão Ramalho Rodrigues, Ana Luisa Calich |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
musculoskeletal diseases myalgia medicine.medical_specialty Paraneoplastic Syndromes Octreotide Scintigraphy Multimodal Imaging Lesion medicine Humans Radiology Nuclear Medicine and imaging Bone pain Tomography Emission-Computed Single-Photon Neoplasms Connective Tissue Osteomalacia medicine.diagnostic_test business.industry Magnetic resonance imaging Organotechnetium Compounds General Medicine medicine.disease Magnetic Resonance Imaging Oncogenic osteomalacia Neoplasms Unknown Primary Female Radiology Radiopharmaceuticals medicine.symptom Tomography X-Ray Computed Nuclear medicine business medicine.drug |
| Zdroj: | Clinical Nuclear Medicine. 40:54-57 |
| ISSN: | 0363-9762 |
| DOI: | 10.1097/rlu.0000000000000341 |
| Popis: | A 32-year-old woman presented with progressive myalgia, bone pain, fatigue, insufficiency hip fractures, high urine phosphate, and low serum phosphate and vitamin D levels. These findings were suggestive of oncogenic osteomalacia. A whole-body Tc-octreotide scintigraphy with SPECT/CT showed uptake on a sclerotic intramedullary lesion in the left medial tibia plateau. MRI depicted a solid lesion. The lesion was surgically removed; the patient became asymptomatic, and follow-up laboratory results normalized. Histopathologic examination revealed a vascular hemangiopericytoma-like tumor, positive for somatostatin receptor (SSR-2). Whole-body Tc-octreotide scintigraphy with SPECT/CT may detect occult oncogenic osteomalacia tumors. |
| Databáze: | OpenAIRE |
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