Pneumonic Plague Cluster, Uganda, 2004
| Autor: | Brook Yockey, Zaccheus Anywaine, Martin E. Schriefer, Christopher Sexton, Scott W. Bearden, J. Erin Staples, Elizabeth M. Begier, Gershim Asiki, Asaph Ogen-Odoi, Jacob L. Kool, Philliam Aleti |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2006 |
| Předmět: |
Adult
Male Microbiology (medical) Pneumonic plague endocrine system Epidemiology Attack rate lcsh:Medicine Disease cluster complex mixtures Bubonic plague plague transmission lcsh:Infectious and parasitic diseases medicine Humans pneumonia Uganda lcsh:RC109-216 Direct fluorescent antibody Plague research biology Transmission (medicine) lcsh:R technology industry and agriculture respiratory system biology.organism_classification medicine.disease Virology eye diseases Infectious Diseases Yersinia pestis Population Surveillance Immunology disease outbreaks Sputum Female Contact Tracing medicine.symptom |
| Zdroj: | Emerging Infectious Diseases, Vol 12, Iss 3, Pp 460-467 (2006) Emerging Infectious Diseases |
| ISSN: | 1080-6059 1080-6040 |
| Popis: | In a case cluster, pneumonic plague transmission was compatible with respiratory droplet rather than aerosol transmission. The public and clinicians have long-held beliefs that pneumonic plague is highly contagious; inappropriate alarm and panic have occurred during outbreaks. We investigated communicability in a naturally occurring pneumonic plague cluster. We defined a probable pneumonic plague case as an acute-onset respiratory illness with bloody sputum during December 2004 in Kango Subcounty, Uganda. A definite case was a probable case with laboratory evidence of Yersinia pestis infection. The cluster (1 definite and 3 probable cases) consisted of 2 concurrent index patient–caregiver pairs. Direct fluorescent antibody microscopy and polymerase chain reaction testing on the only surviving patient's sputum verified plague infection. Both index patients transmitted pneumonic plague to only 1 caregiver each, despite 23 additional untreated close contacts (attack rate 8%). Person-to-person transmission was compatible with transmission by respiratory droplets, rather than aerosols, and only a few close contacts, all within droplet range, became ill. |
| Databáze: | OpenAIRE |
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