Physiological stress reactivity in pediatric cancer survivors treated with chemotherapy

Autor:	Gillian W. White, Shawn G. Rhind, Paul C. Nathan, Jessica E. Caterini, Heather NP Jones, Greg D. Wells
Rok vydání:	2022
Předmět:	Hydrocortisone Tumor Necrosis Factor-alpha Interleukin-8 Hematology Cancer Survivors Oncology Salivary alpha-Amylases Stress Physiological Neoplasms Pediatrics Perinatology and Child Health Humans Survivors Child Saliva Stress Psychological
Zdroj:	Pediatric Blood & Cancer. 69
ISSN:	1545-5017 1545-5009
DOI:	10.1002/pbc.29881
Popis:	Children who experience early life stress demonstrate changes to their stress responses, which may modulate long-term health. Childhood cancer presents significant stress during diagnosis, treatment, and survivorship. We hypothesized that children who have completed chemotherapy treatment for ALL will demonstrate altered hormone patterns in response to a stressor compared with healthy controls. Twelve pediatric ALL survivors and 12 healthy controls completed the Trier Social Stress Test. Salivary samples, heart rate, and self-report ratings of stress were collected at baseline, pretest, and posttest. Between group comparison showed baseline (interleukin [IL]-8) was significantly higher in the survivor group versus controls (survivors: 89.9, 40.1-544.9 pg ml
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c342d965fa66fcdf63bdff6296c5094 https://doi.org/10.1002/pbc.29881 Zobrazit plný text záznamu Plný text