A dynamic reversible phenylboronic acid sensor for real-time determination of protein-carbohydrate interactions on living cancer cells

Autor:	Quanquan Song, Qian Li, Shuang Chao, Xian Chen, Ronghui Li, Yuchao Lu, Teodor Aastrup, Zhichao Pei
Rok vydání:	2022
Předmět:	Materials Chemistry Metals and Alloys Ceramics and Composites General Chemistry Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials
Zdroj:	Chemical communications (Cambridge, England). 58(99)
ISSN:	1364-548X
Popis:	Real-time detection of glycosylation on label-free cancer cell surfaces is of significance for the diagnosis and treatment of cancer. In this work, we have successfully developed a novel dynamic reversible sensor based on pH-sensitive phenylboronic esters to determine in real-time the binding kinetics of protein-carbohydrate interactions on suspension cancer cell surfaces using a quartz crystal microbalance (QCM) technique.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c2ce9dd6baab001f22c0c761cc02dd3 https://pubmed.ncbi.nlm.nih.gov/36444745 Zobrazit plný text záznamu