Dietary Long-Chain Fatty Acids and Cognitive Performance in Older Australian Adults
| Autor: | Amanda J. Patterson, Lesley MacDonald-Wicks, Mark McEvoy, Eliza Magennis, Peter W. Schofield, Karly Zacharia |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Multivariate statistics lcsh:TX341-641 Diet Surveys Article 03 medical and health sciences 0302 clinical medicine Linear regression medicine Humans Cognitive Dysfunction 030212 general & internal medicine Effects of sleep deprivation on cognitive performance Cognitive decline cognitive performance Aged chemistry.chemical_classification Aged 80 and over Nutrition and Dietetics Mini–Mental State Examination medicine.diagnostic_test business.industry Fatty Acids Fatty acid Cognition Middle Aged Mental Status and Dementia Tests Dietary Fats Mini Mental State Examination (MMSE) Diet Audio Recorded Cognitive Screen (ARCS) Cross-Sectional Studies chemistry Quartile Cognitive Aging Multivariate Analysis Linear Models Female fatty acid Hunter Community Study (HCS) New South Wales business lcsh:Nutrition. Foods and food supply 030217 neurology & neurosurgery Food Science Demography |
| Zdroj: | Nutrients Nutrients, Vol 11, Iss 4, p 711 (2019) Volume 11 Issue 4 |
| ISSN: | 2072-6643 |
| Popis: | Convincing evidence exists for the positive effect of an improvement in diet quality on age-related cognitive decline, in part due to dietary fatty acid intake. A cross-sectional analysis of data from the Hunter Community Study (HCS) (n = 2750) was conducted comparing dietary data from a validated Food Frequency Questionnaire (FFQ) with validated cognitive performance measures, Audio Recorded Cognitive Screen (ARCS) and Mini Mental State Examination (MMSE). Adjusted linear regression analysis found statistically significant associations between dietary intake of total n-6 fatty acids (FA), but no other FAs, and better cognitive performance as measured by the ARCS (RC = 0.0043 p = 0.0004 R2 = 0.0084). Multivariate regression analyses of n-6 FA intakes in quartiles showed that, compared with the lowest quartile (179.8&ndash 1150.3 mg), those in the highest quartile (2315.0&ndash 7449.4 mg) had a total ARCS score 2.1 units greater (RC = 10.60466 p = 0.006 R2 = 0.0081). Furthermore, when n-6 FA intake was tested against each of the ARCS domains, statistically significant associations were observed for the Fluency (RC = 0.0011432 p = 0.007 R2 = 0.0057), Visual (RC = 0.0009889 p = 0.034 R2 = 0.0050), Language (RC = 0.0010651 p = 0.047 R2 = 0.0068) and Attention (RC = 0.0011605 p = 0.017 R2 = 0.0099) domains, yet there was no association with Memory (RC = &minus 0.000064 p = 0.889 R2 = 0.0083). No statistically significant associations were observed between FA intakes and MMSE. A higher intake of total n-6 FA, but not other types of FA, was associated with better cognitive performance among a representative sample of older aged Australian adults. |
| Databáze: | OpenAIRE |
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