Echinodorus grandiflorus : Ethnobotanical, phytochemical and pharmacological overview of a medicinal plant used in Brazil
| Autor: | Maria Auxiliadora Coelho Kaplan, Maria Raquel Figueiredo, D. William Provance, André M. Marques |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Phytochemistry Phytochemicals Anti-Inflammatory Agents Toxicology 01 natural sciences 03 medical and health sciences Complex Extracts Animals Humans Medicine Medicinal plants Antihypertensive Agents Alismataceae Plants Medicinal Traditional medicine Echinodorus grandiflorus biology Plant Extracts business.industry General Medicine biology.organism_classification 0104 chemical sciences 010404 medicinal & biomolecular chemistry 030104 developmental biology Phytochemical Ethnobotany Plant species business Brazil Food Science |
| Zdroj: | Food and Chemical Toxicology. 109:1032-1047 |
| ISSN: | 0278-6915 |
| Popis: | Echinodorus grandiflorus (Cham. & Schltdl.) Micheli is a native Brazilian species used in traditional practices for the treatment of several conditions such as inflammatory diseases, arthritis and hypertension. Through a systematic review of the accumulated knowledge about the species E. grandiflorus, the botanical, phytochemistry, ethnobotanical and pharmacological properties of this medicinal plant demonstrates its potential to naturally provide anti-inflammatory and anti-oxidant with a special emphasis on anti-hypertensive and cardioprotective effects. The body of literature reports that the chemical composition of crude E. grandiflorus extracts are notably composed of diterpenoids and flavonoids metabolites. Pharmacological studies have shown that oral treatments using the hydroalcoholic extracts of leaves from this plant has a significant anti-inflammatory, anti-hypertensive, diuretic and cardioprotective effects in rats with no toxicity. The holistic activities of complex extracts are corroborated by the individuals mechanisms of action, as well as, synergistic benefits attributed to the isolated chemical major constituents in this species. In light of the serious health concerns ascribed, it is important to investigate medicinal plant species with histories of traditional use for circulatory problems to meet the growing demands by scientifically validating their use and safety. |
| Databáze: | OpenAIRE |
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