In vitro responses of guinea pig peritoneal macrophages to Legionella pneumophila
| Autor: | R F Berendt, E W Larson, K W Hedlund, V G McGann, F G Shirey, Richard A Kishimoto, J D White |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Cytotoxicity
Immunologic Phagocyte Phagocytosis Immunology Guinea Pigs Virulence Legionella Biology Microbiology Legionella pneumophila Guinea pig medicine Macrophage Animals Cells Cultured Immunity Cellular Macrophages biology.organism_classification Virology In vitro Microscopy Electron Infectious Diseases medicine.anatomical_structure bacteria Parasitology Immunologic Memory Bacteria Research Article |
| Zdroj: | Infection and immunity. 31(3) |
| ISSN: | 0019-9567 |
| Popis: | Transmission and scanning electron microscopy were used to study the phagocytosis of virulent and avirulent strains of Legionella pneumophila. The interaction between L. pneumophila and peritoneal macrophages from normal guinea pigs or from animals that had survived infection was studied. The virulent strains survived and proliferated within the phagocyte after ingestion by either type of macrophage, whereas the avirulent strain of bacteria was killed by normal macrophages. Although the addition of immune serum enhanced phagocytosis, the outcome was the same as with normal serum. |
| Databáze: | OpenAIRE |
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