Diagnosing neuroleukemiosis: Is there a role for 18 F-FDG-PET/CT?

Autor: Montserrat Cortés-Romera, Aida Sabaté-Llobera, J.J. Sánchez-Fernández, Laura Rodriguez-Bel, Cristina Gámez-Cenzano, E. Gamundí-Grimalt
Rok vydání: 2017
Předmět:
Zdroj: Revista Española de Medicina Nuclear e Imagen Molecular (English Edition). 36:396-398
ISSN: 2253-8089
DOI: 10.1016/j.remnie.2017.09.009
Popis: An imaging case is presented on a patient referred to our department for an 18F-FDG-PET/CT, as a paraneoplastic syndrome was suspected due to his clinical situation. He had a history of acute myeloid leukemia (AML) treated two years earlier, with sustained complete remission to date. 18F-FDG-PET/CT findings revealed hypermetabolism in almost all nerve roots, suggesting meningeal spread, consistent with the subsequent MRI findings. Cerebrospinal fluid (CSF) findings confirmed a leptomeningeal reactivation of AML. Although not many studies have evaluated the role of 18F-FDG-PET/CT in leukemia, it is a noninvasive tool for detecting extramedullary sites of disease and a good imaging alternative for those patients on whom an MRI cannot be performed.
Databáze: OpenAIRE