High-Resolution Optical Coherence Tomography Findings of Lisch Epithelial Corneal Dystrophy
| Autor: | Cameron Pole, Sander R. Dubovy, Jose Antonio Bermudez-Magner, Adam Sise, Anat Galor, Carol L. Karp, Madhura Joag |
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| Rok vydání: | 2017 |
| Předmět: |
Male
Pathology medicine.medical_specialty genetic structures High resolution Corneal dystrophy Article Diagnosis Differential 03 medical and health sciences Lisch Epithelial Corneal Dystrophy 0302 clinical medicine Optical coherence tomography medicine Humans Aged Corneal Dystrophies Hereditary medicine.diagnostic_test Extramural business.industry medicine.disease eye diseases Ophthalmology 030221 ophthalmology & optometry sense organs business 030217 neurology & neurosurgery Tomography Optical Coherence |
| Zdroj: | Cornea. 35(3) |
| ISSN: | 1536-4798 |
| Popis: | To describe a case of Lisch epithelial corneal dystrophy (LECD) and present its unique characteristics on high-resolution optical coherence tomography (HR-OCT).A 78-year-old man with whorled corneal epithelial opacities in the right eye was referred for the evaluation of ocular surface squamous neoplasia. Clinical evaluation, photographs, and HR-OCT images of the cornea involved were obtained and scrapings of the affected cornea were sent for histopathologic analysis.Clinically, the patient presented with an opalescent whirling epithelium in a linear pattern encroaching on the visual axis. HR-OCT showed normal thickness epithelial hyperreflectivity of involved cornea without stromal involvement, along with sharply demarcated borders of unaffected tissue. Histopathologic findings demonstrated vacuolated periodic acid-Schiff (PAS) positive cells throughout the epithelial layers consistent with LECD.HR-OCT was able to provide useful information to rule out ocular surface squamous neoplasia and confirm the clinical impression of LECD at the time of clinical examination. HR-OCT shows promise as an adjunctive diagnostic tool for ocular surface lesions and pathologies. |
| Databáze: | OpenAIRE |
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