Osteogenic sarcoma of the maxillary region in a Mexican mestizo population

Autor: Philippe Pasche, Adalberto Mosqueda-Taylor, Verónica Villavicencio-Valencia, Tania Carmona-Luna, Kuauhyama Luna-Ortiz
Rok vydání: 2010
Předmět:
Zdroj: The Journal of craniofacial surgery. 21(6)
ISSN: 1536-3732
Popis: This study analyzed maxillary osteosarcoma in a mestizo population, with particular emphasis on the type of treatment and disease-free and overall survival.This is a retrospective study including all mestizo patients with osteosarcoma of the maxilla seen in a single cancer institution in Mexico during a 20-year period.There were 21 patients. Age ranged from 16 to 76 years (mean, 37.5 y). Mean evolution time to diagnosis was 13 months, with a mean tumor size of 7 × 6 cm2. Surgery was the initial treatment in 19 patients, 17 of whom received adjuvant treatment. Disease-free survival according to surgical margin and overall survival were not statistically significant. Disease-free survival was 29% at 5 years, and overall survival was 50% and 25% at 5 and 10 years, respectively.Osteosarcomas of the maxilla are infrequent lesions that merit early diagnosis and proper treatment because of their rapid evolution. Treatment is currently based on a well-planned surgery with free surgical margins plus adjuvant radiotherapy and/or chemotherapy.
Databáze: OpenAIRE