Osteogenic sarcoma of the maxillary region in a Mexican mestizo population
Autor: | Philippe Pasche, Adalberto Mosqueda-Taylor, Verónica Villavicencio-Valencia, Tania Carmona-Luna, Kuauhyama Luna-Ortiz |
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Rok vydání: | 2010 |
Předmět: |
musculoskeletal diseases
Adult Time Factors Adolescent Population Dentistry Disease-Free Survival Young Adult Sex Factors Ethnicity Medicine Humans education neoplasms Mexico Aged Retrospective Studies Maxillary Neoplasms education.field_of_study Osteosarcoma business.industry Mexican mestizo Age Factors Retrospective cohort study General Medicine Middle Aged medicine.disease Neoadjuvant Therapy Osteotomy Survival Rate Treatment Outcome Otorhinolaryngology Chemotherapy Adjuvant Maxilla Surgery Radiotherapy Adjuvant Sarcoma Neoplasm Recurrence Local business Follow-Up Studies |
Zdroj: | The Journal of craniofacial surgery. 21(6) |
ISSN: | 1536-3732 |
Popis: | This study analyzed maxillary osteosarcoma in a mestizo population, with particular emphasis on the type of treatment and disease-free and overall survival.This is a retrospective study including all mestizo patients with osteosarcoma of the maxilla seen in a single cancer institution in Mexico during a 20-year period.There were 21 patients. Age ranged from 16 to 76 years (mean, 37.5 y). Mean evolution time to diagnosis was 13 months, with a mean tumor size of 7 × 6 cm2. Surgery was the initial treatment in 19 patients, 17 of whom received adjuvant treatment. Disease-free survival according to surgical margin and overall survival were not statistically significant. Disease-free survival was 29% at 5 years, and overall survival was 50% and 25% at 5 and 10 years, respectively.Osteosarcomas of the maxilla are infrequent lesions that merit early diagnosis and proper treatment because of their rapid evolution. Treatment is currently based on a well-planned surgery with free surgical margins plus adjuvant radiotherapy and/or chemotherapy. |
Databáze: | OpenAIRE |
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