A new lignan from the flowers of Hibiscus sabdariffa L. (Malvaceae)
| Autor: | Quang Ton That, Ngoc Vinh Huynh, Lien Thi My Do, Huu Phuc Dang, Duc Minh Nguyen Huu, Truong Van Nguyen Thien, Thanh Tien Nguyen, Phu Hoang Dang, Kim Thuy Tran |
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| Rok vydání: | 2019 |
| Předmět: |
Lignan
Antioxidant biology Traditional medicine 010405 organic chemistry Chemistry medicine.medical_treatment Hibiscus sabdariffa Organic Chemistry Absolute configuration Plant Science biology.organism_classification 01 natural sciences Biochemistry 0104 chemical sciences Analytical Chemistry 010404 medicinal & biomolecular chemistry chemistry.chemical_compound medicine Malvaceae |
| DOI: | 10.6084/m9.figshare.9891467.v1 |
| Popis: | From MeOH-soluble fraction of the flowers of Hibiscus sabdariffa (Malvaceae), one new lignan, (+)-4-O-methyl-5′-methoxy-secoisolariciresinol (1), together with four known compounds (2–5) were isolated. The structures were elucidated based on NMR spectroscopic analysis. The absolute configuration of 1 was determined based on the Cotton effects in the CD spectrum. Compounds 1, 3 and 4 showed antioxidant activities with the SC50 values of 56.9, 19.3 and 22.7 µM, respectively. |
| Databáze: | OpenAIRE |
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