Oocyte in vitro maturation in normo-ovulatory women
| Autor: | Amalia Epis, Rubens Fadini, Mario Mignini Renzini, Giovanni Coticchio, Mariabeatrice Dal Canto, Ilaria Caliari, Marilena Crippa, Claudio Brigante |
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| Rok vydání: | 2013 |
| Předmět: |
Ovulation
Pregnancy Rate medicine.medical_treatment Stimulation Cryopreservation Andrology Human fertilization Ovulation Induction Pregnancy medicine Humans Embryo Implantation urogenital system business.industry Obstetrics and Gynecology Oocyte medicine.disease In Vitro Oocyte Maturation Techniques In vitro maturation Pregnancy rate medicine.anatomical_structure Reproductive Medicine embryonic structures Oocytes Female Ovulation induction business |
| Zdroj: | Fertility and Sterility. 99:1162-1169 |
| ISSN: | 0015-0282 |
| DOI: | 10.1016/j.fertnstert.2013.01.138 |
| Popis: | Objective To review the scientific literature concerning the application of oocyte in vitro maturation (IVM) as a treatment for normo-ovulatory women. Design Critical evaluation and comparison of the most relevant clinical studies. Setting Public IVF unit. Patient(s) Normo-ovulatory women. Intervention(s) Oocyte IVM and cryopreservation. Main Outcome Measure(s) Maturation, fertilization, implantation, and pregnancy rates. Result(s) Maturation rates in vitro are suboptimal and influenced by several factors. IVM oocytes fertilize and undergo development in vitro with rates similar to in vivo matured control oocytes. In IVM cycles implantation and pregnancy rates are lower compared with controlled ovarian stimulation treatments, but accurate patient selection can improve IVM clinical outcome. Conclusion(s) In normal responders, IVM does not reach success rates similar to conventional ovarian stimulation regimens. However, it represents a milder approach to assisted reproduction treatment and an alternative intervention for specific conditions. |
| Databáze: | OpenAIRE |
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