A disposable flexible skin patch for clinical optical perfusion monitoring at multiple depths
| Autor: | Daniel E. Fernandez, Matthew J. Podolsky, Norman A. Paradis, Stephen E. Feinberg, Brent B. Ward, Mary Ann Mycek, Christopher J. Stapels, Daniel R. McAdams, Noah J. Kolodziejski, Christopher P. Johnson, Michael J. Joyner, Mark Vartarian, Seung Yup Lee, James F. Christian, Dana Farkas, Urmi Parikh |
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| Rok vydání: | 2016 |
| Předmět: |
Optical fiber
Materials science Diffuse reflectance infrared fourier transform business.industry 030208 emergency & critical care medicine Diffuse correlation spectroscopy 01 natural sciences Article Skin patch Shock (mechanics) law.invention 010309 optics 03 medical and health sciences 0302 clinical medicine Lower body Optics law 0103 physical sciences Monitoring methods business Perfusion Biomedical engineering |
| Zdroj: | SPIE Proceedings. |
| ISSN: | 0277-786X |
| Popis: | Stable, relative localization of source and detection fibers is necessary for clinical implementation of quantitative optical perfusion monitoring methods such as diffuse correlation spectroscopy (DCS) and diffuse reflectance spectroscopy (DRS). A flexible and compact device design is presented as a platform for simultaneous monitoring of perfusion at a range of depths, enabled by precise location of optical fibers in a robust and secure adhesive patch. We will discuss preliminary data collected on human subjects in a lower body negative pressure model for hypovolemic shock. These data indicate that this method facilitates simple and stable simultaneous monitoring of perfusion at multiple depths and within multiple physiological compartments. |
| Databáze: | OpenAIRE |
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