Advanced meta-analyses comparing the three surgical techniques total disc replacement, anterior stand-alone fusion and circumferential fusion regarding pain, function and complications up to 3 years to treat lumbar degenerative disc disease
| Autor: | Tobias Bohn, Susanne Annette Jennifer Lang, Karin Büttner-Janz, Stephanie Roll, Luisa Barleben, Matthias Pumberger |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Total Disc Replacement Visual analogue scale medicine.medical_treatment Pain Intervertebral Disc Degeneration law.invention Degenerative disc disease 03 medical and health sciences 0302 clinical medicine Lumbar Randomized controlled trial law medicine Humans Orthopedics and Sports Medicine Prospective Studies Prospective cohort study 030222 orthopedics Lumbar Vertebrae business.industry medicine.disease Surgery Oswestry Disability Index Spinal Fusion Treatment Outcome Spinal fusion Inclusion and exclusion criteria business 030217 neurology & neurosurgery |
| Zdroj: | European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 30(12) |
| ISSN: | 1432-0932 |
| Popis: | The purpose of our meta-analyses is to find the most appropriate surgical technique treating lumbar degenerative disc disease (DDD). Spinal fusion is the conventional treatment for lumbar DDD. Total disc replacement (TDR) has been developed to avoid negative effects of fusions by preserving functionality. To our knowledge, there is no evaluation comparing meta-analytically the clinical results of three different surgical techniques with same inclusion and exclusion criteria for treating DDD. The surgical techniques TDR, anterior lumbar interbody fusion (ALIF) and circumferential fusion (CFF) are pairwise meta-analytically compared. Primary outcomes are pain measured by the Visual Analogue Scale (VAS) and function measured by the Oswestry Disability Index (ODI). Secondary outcomes are the mean number of complications per case (MNOC) at surgery and follow-up and the overall MNOC. In our systematic search, we found finally six prospective studies with the minimum follow-up of two years: four randomized controlled trials and two cohort studies. In VAS and ODI, TDR is proved to be superior to ALIF and CCF (p |
| Databáze: | OpenAIRE |
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